Ivan Rusyn Selected Research

Peroxisome Proliferators

3/2009	Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver.
12/2007	Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.
12/2007	Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.
8/2007	WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.

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Ivan Rusyn Research Topics

Disease

37	Neoplasms (Cancer) 07/2022 - 02/2005
19	Carcinogenesis 12/2020 - 05/2006
14	Non-alcoholic Fatty Liver Disease 11/2022 - 10/2010
9	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 01/2005
7	Fatty Liver 01/2021 - 11/2005
7	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 03/2013
6	Inflammation (Inflammations) 01/2018 - 03/2007
5	Cardiotoxicity 01/2022 - 01/2013
5	Necrosis 01/2021 - 09/2007
5	Fibrosis (Cirrhosis) 11/2016 - 03/2002
4	Carcinoma (Carcinomatosis) 09/2007 - 05/2006
3	Hepatomegaly 01/2021 - 05/2006
3	Liver Diseases (Liver Disease) 01/2020 - 11/2005
3	Liver Neoplasms (Liver Cancer) 01/2018 - 05/2006
3	Hypoxia (Hypoxemia) 10/2008 - 03/2002
3	Adenoma (Adenomas) 08/2007 - 01/2005
2	Alcoholic Hepatitis 01/2020 - 01/2020
2	Infections 01/2020 - 01/2013
2	Insulin Resistance 01/2020 - 10/2010
2	Genomic Instability 03/2016 - 12/2014
2	Liver Cell Adenoma (Hepatocellular Adenoma) 02/2011 - 09/2007
2	Hypertrophy 12/2007 - 09/2007
2	Ischemia 06/2006 - 03/2002
2	Reperfusion Injury 06/2006 - 03/2002
1	Leukemia 10/2021
1	Heart Diseases (Heart Disease) 01/2021
1	COVID-19 01/2021
1	Colonic Neoplasms (Colon Cancer) 12/2020
1	Portal Hypertension 01/2020
1	Body Weight (Weight, Body) 01/2019
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2019
1	Idiopathic Pulmonary Fibrosis 01/2018

Drug/Important Bio-Agent (IBA)

14	CarcinogensIBA 01/2022 - 01/2007
10	Pharmaceutical PreparationsIBA 01/2022 - 01/2005
8	Choline (Choline Chloride)IBA 01/2020 - 07/2005
7	MicroRNAs (MicroRNA)IBA 10/2017 - 01/2010
6	Tetrachloroethylene (Tetrachloroethene)IBA 01/2021 - 01/2017
6	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019 - 11/2012
5	1,3-butadiene (divinyl)IBA 07/2022 - 01/2018
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 03/2007
5	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2017 - 03/2013
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2007
4	Ethanol (Ethyl Alcohol)IBA 01/2020 - 02/2005
4	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 09/2008
4	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 01/2018 - 06/2014
4	Peroxisome ProliferatorsIBA 03/2009 - 08/2007
3	DNA AdductsIBA 11/2021 - 09/2005
3	LipidsIBA 12/2020 - 11/2005
3	Methionine (L-Methionine)FDA Link 01/2020 - 01/2017
3	Trichloroethylene (Trichloroethene)IBA 01/2019 - 01/2015
3	CytosineIBA 01/2019 - 09/2008
3	XenobioticsIBA 01/2018 - 01/2017
3	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2013 - 02/2007
3	Diethylhexyl Phthalate (DEHP)IBA 04/2012 - 05/2006
3	PPAR alphaIBA 03/2009 - 01/2005
3	CytokinesIBA 12/2008 - 06/2006
2	Sucrose (Saccharose)IBA 11/2022 - 01/2020
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2021 - 01/2005
2	GW 7647IBA 01/2021 - 01/2021
2	Vincristine (Oncovin)FDA LinkGeneric 12/2020 - 01/2020
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020 - 04/2007
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 10/2010
2	ArsenicIBA 01/2019 - 01/2013
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 03/2009
2	Lysine (L-Lysine)FDA Link 12/2014 - 06/2014
2	Histones (Histone)IBA 12/2014 - 06/2014
2	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 08/2013 - 11/2011
2	CarbonIBA 06/2013 - 07/2012
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2013 - 07/2009
2	Phenobarbital (Luminal)FDA Link 03/2009 - 09/2007
2	Constitutive Androstane ReceptorIBA 03/2009 - 09/2007
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 06/2007 - 03/2002
1	Epoxy Compounds (Epoxides)IBA 11/2021
1	SoilIBA 01/2021
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021
1	Butyrates (Butyrate)IBA 12/2020
1	Fluorouracil (Carac)FDA LinkGeneric 12/2020
1	Sorafenib (BAY 43-9006)FDA Link 12/2020
1	3- (8- amino- 1- (2- phenylquinolin- 7- yl)imidazo(1,5- a)pyrazin- 3- yl)- 1- methylcyclobutanolIBA 01/2020
1	CholesterolIBA 01/2020
1	Cisplatin (Platino)FDA LinkGeneric 01/2020
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	Lipocalin-2IBA 01/2020
1	3,5- diethoxycarbonyl- 1,4- dihydrocollidineIBA 01/2020
1	HDL LipoproteinsIBA 01/2020
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	Methotrexate (Mexate)FDA LinkGeneric 01/2020
1	Glutathione (Reduced Glutathione)IBA 01/2019
1	Glycine N-Methyltransferase (Glycine Sarcosine N-Methyltransferase)IBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	AdenosylhomocysteinaseIBA 01/2018

Therapy/Procedure

5	Therapeutics 01/2021 - 11/2016
2	Drug Therapy (Chemotherapy) 08/2021 - 09/2014
2	Fat-Restricted Diet (Diet, Fat Restricted) 01/2017 - 01/2017
1	Precision Medicine 08/2021
1	Withholding Treatment 01/2020
1	Intraperitoneal Injections 01/2019